MS Fatigue Assessment

How is fatigue affecting your life?

The Fatigue Severity Scale (FSS) is a clinically validated 9-question assessment used in multiple sclerosis research worldwide. It takes less than 2 minutes.

You'll receive your personal score and see how it compares to other patients — based on published clinical data.

9 questions
Under 2 minutes
Free & confidential
ℹ️

This assessment is for informational purposes only and does not constitute medical advice or diagnosis. Consult your physician with any health concerns.

Your progress 0 of 9 answered
9 Questions

Rate each statement from 1 to 7

Base your answers on how you have felt during the past week.

1 = Strongly Disagree 7 = Strongly Agree
Your FSS Score
Total: — / 63

How you compare to other patients

Healthy Controls
MS Patients
Your Score
Clinical Evidence

In the PhoCIS clinical trial, participants who received NB-UVB phototherapy showed a reduction in fatigue scores at 6 months that met the minimally important difference — the threshold researchers use to determine whether a change is clinically meaningful, not just a statistical fluctuation. The control group showed the opposite trend over the same period.

The PhoCIS trial (Hart et al., 2018) was a randomised controlled study of narrowband UVB phototherapy in patients with Clinically Isolated Syndrome (CIS) — an early-stage demyelinating condition and recognised precursor to MS.

Fatigue at 6 months: The phototherapy group's FSS score dropped from a median of 3.7 to 2.8 — a change of 0.9 points. The accepted minimally important difference (MID) for the FSS is 0.45 points, meaning the phototherapy group's improvement was twice the threshold for clinical relevance.

Sources

  1. Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The Fatigue Severity Scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989;46(10):1121–3. PMID: 2803071.
  2. Valko PO, Bassetti CL, Bloch KE, Held U, Baumann CR. Validation of the Fatigue Severity Scale in a Swiss cohort. Sleep. 2008;31(11):1601–7. (Source for MS, Ischemic Stroke, and Sleep Disorders population distributions.)
  3. Hart PH, Jones AP, Trend S, et al. A randomised, controlled clinical trial of narrowband UVB phototherapy for clinically isolated syndrome: The PhoCIS study. Multiple Sclerosis Journal — Experimental, Translational and Clinical. 2018. doi:10.1177/2055217318773112. PMC: 5954316.
  4. Naik H, Voznyuk I, Murray M, et al. Evaluating fatigue in patients recovering from COVID-19: validation of the Fatigue Severity Scale and single item screening questions. Health Qual Life Outcomes. 2022;20(1):170. PMID: 36575437. (Source for Long COVID population distribution.)
  5. Lu J, et al. Fatigue in systemic lupus erythematosus: associations with disease activity and quality of life. Front Psychol. 2024. doi:10.3389/fpsyg.2024.1376257. (Source for Lupus/SLE population distribution.)
  6. Krupp LB, et al. (1993). FSS normative data in CFS. Cited in: Jason LA, et al. Fatigue Scales and Chronic Fatigue Syndrome: Issues of Sensitivity and Specificity. Disability Studies Quarterly. 2011;31(1). doi:10.18061/dsq.v31i1.1375. (Source for CFS/ME-CFS population distribution.)
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Help future patients like you

We're building a database of fatigue data from people living with autoimmune conditions to better understand how phototherapy helps. Your data is kept private and used only in aggregate.

This is completely optional — you can skip straight to your results.

🔒 Your responses are anonymous and never sold or shared with third parties. Initials, if provided, are used only to distinguish repeat submissions.

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